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The purpose of this systematic review was to compare corticosteroid injections with non-steroidal anti-inflammatory drug (NSAID) injections for musculoskeletal pain. We included reviews published in English as full-text articles up to December 30, 2015. Articles were evaluated using the Cochrane systematic review tool, review buysteroids.com. We also performed bivariable analysis to compare the rate of adverse events for the subgroup of cases in which the NSAID was administered with that in cases where the corticosteroid was given. The results are consistent with previous studies showing no difference in the incidence of adverse events after administration of either drug in comparison to placebo [20,31,37–39], buysteroids.com review. Furthermore, no evidence was found to suggest that the corticosteroid produced greater analgesia, anabolic steroids mixed with other drugs. We found that the risk of serious adverse events in the latter group was nearly double between the two groups as compared to the subgroup of cases in which the NSAID was administered, whereas it was not increased among the other groups. The most frequent serious adverse events after corticosteroid injections were swelling, bruising and/or swelling of the fingers. These events also occurred at higher rates in the corticosteroid group whereas the number of serious adverse events in the placebo group were similar, bodybuilding steroids deaths. The rate of side effects also increased in the corticosteroid group and was almost 10 to 16 times that in the placebo groups, bodybuilding steroids deaths. Therefore, we conclude that either corticosteroid injection or placebo did not result in a higher pain burden in musculoskeletal symptoms that include the hands without any other specific symptoms that include the head, neck and back. In conclusion, this systematic review of reviews shows no difference in the risk of serious adverse events in patients receiving either of these two analgesic agents in terms of adverse events, anabolic steroid use in males.
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